Talk:Downregulation and upregulation

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): ErinYL. Peer reviewers: ErinYL.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 19:48, 16 January 2022 (UTC)

Suggestion

Hello! I've added part of the overview and citations that this page was needed, and re-organized the page a little bit because I am really interested in this field. I was going to add some more to it, but was not sure if I could complete it. I am planning to revisit this page so that I can add more stuff, but for now, this is my best. I ADDED links that are related to this page too. If anyone could add some facts about how receptor downregulation affects on the drug-addiction, it'd be awesome. I know there is a page Addiction which covers about it a little, but I thought it'd be nice to have some detailed information outside of that page. And I agree, this page is really inconsistent. I would say maybe adding more examples of receptor downregulation and upregulation will improve the overall quality. ErinYL (talk) 21:46, 20 November 2016 (UTC)

Inconsistency -- why is the body of the article only about insulin?

why is the body of the article only about insulin? I don't have enough expertise to fix the article, but I know that there are all sorts of other non-insulin-related instances of upregulation and downregulation, e.g., 5ht2 downregulation that occurs after treatment with certain antidepressants.PStrait (talk) 21:45, 30 June 2009 (UTC)

I second this, I'm surprised that even 5 years after someone made this point, it's still only about insulin :P. All receptors experience up/down regulation, and insulin is really the least relevant example. I'd say most people looking into receptor regulation are probably considering it from the perspective of drug addiction/tolerance, so it seems odd that dopamine, seratonin, etc aren't mentioned. I may fix this when I have time, though I have no official credentials, it would be best for a professional to write the article. LiamSP (talk) 19:32, 6 March 2013 (UTC)

I think it is mostly diabetics that are interested in this topic. As for type-1-diabetes the dosage of insulin is a daily game with up- and downregulation. The amount of insulin you need for a certain kind of food not only depends on the food itself but also on the amount of insulin you used the days before. 194.118.150.177 (talk) 13:42, 5 August 2013 (UTC)

The number of a component

This makes no sense: "Downregulation is the process by which a cell decreases the number of a cellular component...." How are cellular components numbered, and what's the significance of those numbers? If it's the number of receptors or molecules that matters, that should be stated explicitly. Unfree (talk) 05:51, 21 March 2008 (UTC)

the receptor down regulation is not specific for only insulin!! —Preceding unsigned comment added by 203.128.26.216 (talk) 06:11, 6 March 2009 (UTC)

Inline citations preferred to manually adding items to "references" section.

There is a good explaination available on how the {{reflist}} template can be used: Wikipedia:Referencing for beginners ... To elaborate, the way references are generally used on wikipedia, the {{reflist}} template will automatically generate the references section at the bottom of an article from the wikimarkup of supporting citations / references is placed inline next to each fact that is able to be verified by a published book, scientific journal, etc. --Kuzetsa (talk) 17:09, 10 October 2008 (UTC)

In this case, the "Inline references" section for WP:Citing sources further explains how to bring the quality up to "Good article" status. --Kuzetsa (talk) 17:37, 10 October 2008 (UTC)